Disseminated paracoccidioidomycosis with meningitis without pulmonary involvement

Authors

  • Vladimir Rosmel Peredo Chambi Instituto de Infectologia Emilio Ribas, - São Paulo - São Paulo - Brasil.
  • José Ernesto Vidal Instituto de Infectologia Emilio Ribas, - São Paulo - São Paulo - Brasil.
  • Marcelo Nascimento Burattini Universidade Federal de São Paulo, Departamento de Doenças Infecciosas e Parasitarias - São Paulo - São Paulo - Brasil.

DOI:

https://doi.org/10.5935/2764-734X.e20250249

Keywords:

Central Nervous System, Toxoplasmosis Cerebral;, Paracoccidioidomycosis, Acquired Immunodeficiency Syndrome, Case Report

Abstract

Paracoccidioidomycosis is the most common deep mycosis in Latin America, but it is uncommon in people living with HIV/AIDS, particularly neuroparacoccidioidomycosis. This study reports the case of a 33-year-old man, infected with HIV and with severe immunosuppression. The patient presented the “mixed form” of paracoccidioidomycosis, defined by the concomitant presence of acute/subacute and chronic forms, however without pulmonary involvement. The main differential in this context was cerebral toxoplasmosis, with the final diagnosis being obtained by histological analysis of the lymph node and oral mucosa, as well as through an immunological reaction in the cerebrospinal fluid.

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Published

2025-04-28

How to Cite

Chambi, V. R. P., Vidal, J. E., & Burattini, M. N. (2025). Disseminated paracoccidioidomycosis with meningitis without pulmonary involvement. Infections in Evidence, 4, e20250249. https://doi.org/10.5935/2764-734X.e20250249

Issue

Vol. 4 (2025)

Section

Case Reports

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