Atypical presentation of erythema induratum of Bazin
DOI:
https://doi.org/10.5935/2764-734X.e20250660Keywords:
Tuberculose Extrapulmonar, Tuberculose Cutânea, Paniculite, Relatos De CasosAbstract
Cutaneous involvement in tuberculosis is uncommon and includes several clinical entities, including the erythema induratum of Bazin, whose classic presentation involves purplish nodules or nodular plaques that tend to ulcerate and evolve into outbreaks. In this report, we describe a case of atypical clinical presentation of erythema induratum of Bazin in a 17-year-old patient who presented with crusty, scaly and hyperemic lesions on her legs, which had been progressing for approximately 3 years without signs of systemic involvement. Diagnostic investigation corroborated this hypothesis through the epidemiological link and compatible anatomopathological studies and by ruling out the most common differential diagnoses. The patient showed clinical improvement after starting the anti-tuberculosis medications, and the lesions completely disappeared at the end of the treatment.
Downloads
References
Brito AC, Oliveira CMM, Unger DA, Bittencourt MJS. Cutaneous tuberculosis: epidemiological, clinical, diagnostic and therapeutic update. An Bras Dermatol. 2022 Mar/Apr;97(2):129-44. DOI: 10.1016/j.abd.2021.07.004
Chen Q, Chen W, Hao F. Cutaneous tuberculosis: A great imitator. Clin Dermatol. 2019 May/Jun;37(3):192-9. DOI: 10.1016/j.clindermatol.2019.01.008
Nguyen KH, Alcantara CA, Glassman I, May N, Mundra A, Mukundan A, et al. Cutaneous Manifestations of Mycobacterium tuberculosis: A Literature Review. Pathogens. 2023 Jul;12(7):920. DOI: 10.3390/pathogens12070920
Mascaró JM, Baselga E. Erythema induratum of bazin. Dermatol Clin. 2008 Oct;26(4):439-45. DOI: 10.1016/j.det.2008.05.007
Babu AK, Krishnan P, Dharmaratnam AD. Erythema Induratum of Bazin – Tuberculosis in disguise. J Dermatol Dermatol Surg Jan;2015;19(1):66-8. DOI: 10.1016/j.jdds.2014.03.001
Dharmadji HP, Suwarsa O, Sutedja E, Pangastuti M, Gunawan H, Makarti K. Erythema Induratum of Bazin Accompanied by Atrophy of the Subcutaneous Fat. Int Med Case Rep J. 2021 Nov 15;14:777-81. DOI: 10.2147/IMCRJ.S336088
Tehrany YA, Toutous-Trellu L, Trombert V, Reny JL, Kaya G, Prendki V. A Case of Tuberculous Granulomatous Panniculitis without Vasculitis. Case Rep Dermatol. 2015 Jul;7(2):141-5. DOI: 10.1159/000435831
Magalhães TS, Dammert VG, Samorano LP, Litvoc MN, Nico MMS. Erythema induratum of Bazin: Epidemiological, clinical and laboratorial profile of 54 patients. J Dermatol. 2018 May;45(5):628-69. DOI: 10.1111/1346-8138.14260
Maio P, Vieira R, Pacheco A, Cardoso J. Eritema Induratum de Bazin – um caso numa doente com tuberculose ganglionar activa. J Port Soc Dermatol Venereol. 2013;70(1):131. DOI: 10.29021/spdv.70.1.50
Daher EF, Silva Júnior GB, Pinheiro HC, Oliveira TR, Vilar ML, Alcântara KJ. Erythema induratum of Bazin and renal tuberculosis: report of an association. Rev Inst Med Trop Sao Paulo. 2004 Sep/Oct;46(5):295-8. DOI: 10.1590/s0036-46652004000500013
Sayeed SJB, Hossain MA, Moniruzzaman M, Malik AS, Rahman S. Erythema Induratum of Bazin, a Rare Manifestation of Cutaneous Tuberculosis: A Case Report. J Med. 2022;23(2):165-8. DOI: 10.3329/jom.v23i2.60635
Segura S, Pujol RM, Trindade F, Requena L. Vasculitis in erythema induratum of Bazin: A histopathologic study of 101 biopsy specimens from 86 patients. J Am Acad Dermatol. 2008 Nov;59(5):839-51. DOI: 10.1016/j.jaad.2008.07.030
Brandão Neto RA, Carvalho JF. Erythema induratum of Bazin associated with Addison’s disease: first description. Sao Paulo Med J. 2012;130(6):405-8. DOI: 10.1590/S1516-31802012000600008
Yang K, Li T, Zhu X, Zou Y, Liu D. Erythema induratum of Bazin as an indicative manifestation of cavitary tuberculosis in an adolescent: a case report. BMC Infect Dis. 2021 Aug;21(1):747. DOI: 10.1186/s12879-021-06454-4
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Infections in Evidence

This work is licensed under a Creative Commons Attribution 4.0 International License.
The Copyright Transfer Agreement also understands that the authors guarantee that the respective Case Report has never been published in another communication vehicle or scientific journal. Papers presented at meetings and/or scientific congresses may be published in the electronic Journal INFECTIONS IN EVIDENCE - Case Reports, provided they have not been published in whole or in part in their Proceedings or Annals in the format of a complete article including images, discussion and bibliographic references, or that they have not been assigned a specific DOI number.














