Apresentação atípica do eritema indurado de Bazin

Atypical presentation of erythema induratum of Bazin

Authors

  • Bruno Correia Ernandes Instituto Clemente Ferreira
  • Jequélie Cássia Gomes Duarte Instituto Clemente Ferreira
  • Denise do Socorro da Silva Rodrigues Instituto Clemente Ferreira

DOI:

https://doi.org/10.5935/2764-734X.e20250660

Keywords:

Tuberculose Extrapulmonar, Tuberculose Cutânea, Paniculite, Relatos De Casos

Abstract

O acometimento cutâneo pela tuberculose é incomum e compreende diversas entidades clínicas, dentre elas o eritema indurado de Bazin, cuja apresentação clássica envolve nódulos violáceos ou placas nodulares, com tendência à ulceração e com evolução em “surtos”. Neste relato descrevemos um caso de apresentação clínica atípica do eritema indurado de Bazin numa paciente de 17 anos que apresentava lesões crostosas, descamativas e hiperemiadas em membros inferiores, com evolução progressiva há cerca de três anos e sem quaisquer sinais de comprometimento sistêmico. A investigação diagnóstica corroborou a hipótese aventada através de vínculo epidemiológico e estudo anatomopatológico compatível, bem como por descartar os diagnósticos diferenciais mais comuns. A paciente evoluiu com melhora clínica após o início do tratamento da tuberculose e obteve involução completa das lesões ao final do esquema terapêutico específico.

References

Brito AC, Oliveira CMM, Unger DA, Bittencourt MJS. Cutaneous tuberculosis: epidemiological, clinical, diagnostic and therapeutic update. An Bras Dermatol. 2022 Mar/Apr;97(2):129-44. DOI: 10.1016/j.abd.2021.07.004

Chen Q, Chen W, Hao F. Cutaneous tuberculosis: A great imitator. Clin Dermatol. 2019 May/Jun;37(3):192-9. DOI: 10.1016/j.clindermatol.2019.01.008

Nguyen KH, Alcantara CA, Glassman I, May N, Mundra A, Mukundan A, et al. Cutaneous Manifestations of Mycobacterium tuberculosis: A Literature Review. Pathogens. 2023 Jul;12(7):920. DOI: 10.3390/pathogens12070920

Mascaró JM, Baselga E. Erythema induratum of bazin. Dermatol Clin. 2008 Oct;26(4):439-45. DOI: 10.1016/j.det.2008.05.007

Babu AK, Krishnan P, Dharmaratnam AD. Erythema Induratum of Bazin – Tuberculosis in disguise. J Dermatol Dermatol Surg Jan;2015;19(1):66-8. DOI: 10.1016/j.jdds.2014.03.001

Dharmadji HP, Suwarsa O, Sutedja E, Pangastuti M, Gunawan H, Makarti K. Erythema Induratum of Bazin Accompanied by Atrophy of the Subcutaneous Fat. Int Med Case Rep J. 2021 Nov 15;14:777-81. DOI: 10.2147/IMCRJ.S336088

Tehrany YA, Toutous-Trellu L, Trombert V, Reny JL, Kaya G, Prendki V. A Case of Tuberculous Granulomatous Panniculitis without Vasculitis. Case Rep Dermatol. 2015 Jul;7(2):141-5. DOI: 10.1159/000435831

Magalhães TS, Dammert VG, Samorano LP, Litvoc MN, Nico MMS. Erythema induratum of Bazin: Epidemiological, clinical and laboratorial profile of 54 patients. J Dermatol. 2018 May;45(5):628-69. DOI: 10.1111/1346-8138.14260

Maio P, Vieira R, Pacheco A, Cardoso J. Eritema Induratum de Bazin – um caso numa doente com tuberculose ganglionar activa. J Port Soc Dermatol Venereol. 2013;70(1):131. DOI: 10.29021/spdv.70.1.50

Daher EF, Silva Júnior GB, Pinheiro HC, Oliveira TR, Vilar ML, Alcântara KJ. Erythema induratum of Bazin and renal tuberculosis: report of an association. Rev Inst Med Trop Sao Paulo. 2004 Sep/Oct;46(5):295-8. DOI: 10.1590/s0036-46652004000500013

Sayeed SJB, Hossain MA, Moniruzzaman M, Malik AS, Rahman S. Erythema Induratum of Bazin, a Rare Manifestation of Cutaneous Tuberculosis: A Case Report. J Med. 2022;23(2):165-8. DOI: 10.3329/jom.v23i2.60635

Segura S, Pujol RM, Trindade F, Requena L. Vasculitis in erythema induratum of Bazin: A histopathologic study of 101 biopsy specimens from 86 patients. J Am Acad Dermatol. 2008 Nov;59(5):839-51. DOI: 10.1016/j.jaad.2008.07.030

Brandão Neto RA, Carvalho JF. Erythema induratum of Bazin associated with Addison’s disease: first description. Sao Paulo Med J. 2012;130(6):405-8. DOI: 10.1590/S1516-31802012000600008

Yang K, Li T, Zhu X, Zou Y, Liu D. Erythema induratum of Bazin as an indicative manifestation of cavitary tuberculosis in an adolescent: a case report. BMC Infect Dis. 2021 Aug;21(1):747. DOI: 10.1186/s12879-021-06454-4

Downloads

Published

2025-07-29

How to Cite

Ernandes, B. C., Duarte, J. C. G., & Rodrigues, D. do S. da S. (2025). Apresentação atípica do eritema indurado de Bazin: Atypical presentation of erythema induratum of Bazin. Infections in Evidence, 4, e20250660. https://doi.org/10.5935/2764-734X.e20250660

Issue

Vol. 4 (2025)

Section

Case Reports

License

Copyright (c) 2025 Infections in Evidence

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

The Copyright Transfer Agreement assumes that the authors are the legitimate holders of the copyright of the Case Report in question, without infringing any copyright, trademark or patent of others. In this way, they transfer all rights to this manuscript or any revision, version or translation of it to the Journal, including here the exclusivity of its eventual commercialization, provided that in accordance with ethical and moral precepts and relevant Brazilian legislation. All articles in the INFECTIONS IN EVIDENCE Journal are published under the terms of international license 4.0 of the Creative Commons Attribution, which allows users to freely read, download, share and adapt cultural and scientific productions, provided that due credit is given to the original authors and publication.
The Copyright Transfer Agreement also understands that the authors guarantee that the respective Case Report has never been published in another communication vehicle or scientific journal. Papers presented at meetings and/or scientific congresses may be published in the electronic journal INFECTIOUS DISEASES IN EVIDENCE - Case Reports, provided that they have not been published in whole or in part in their Proceedings or Annals.