Doença de Castleman multicêntrica em paciente infectado pelo vírus da imunodeficiência humana
DOI:
https://doi.org/10.5935/2764-734X.e202205010Palavras-chave:
Hiperplasia do Linfonodo Gigante, Linfoma Relacionado a AIDS, Herpesvirus Humano 8, Síndrome Inflamatória da Reconstituição Imune, Sarcoma de KaposiResumo
Doença de Castleman consiste num distúrbio linfoproliferativo raro com apresentações clínicas, histológicas e etiológicas distintas, podendo se apresentar como linfadenopatia localizada ou doença sistêmica. A apresentação da Doença de Castleman multicêntrica tem associação com herpes vírus humano-8 sobretudo em pacientes infectados pelo vírus da imunodeficiência humana e ocasionalmente é encontrado com Sarcoma de Kaposi. Apresentamos um caso pouco descrito na literatura de um homem de 41 anos com diagnóstico recente de infecção pelo vírus da imunodeficiência humana e elevada carga viral que evoluiu com linfonodomegalia periférica associada a Doença de Castleman multicêntrica e Sarcoma de Kaposi após o início de terapia antirretroviral.
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